| Rank | Name | Opp. | Venue | Date | |||
| 1 | CH Gayle (WI) | 117 | (57b) | SAf | Johannesburg | ICC World Twenty20 | 11 Sep 2007 |
| 2 | RT Ponting (Aus) | 98* | (55b) | NZ | Auckland | Only Twenty20 International | 17 Feb 2005 |
| 3 | TM Dilshan (SL) | 96* | (57b) | WI | The Oval | ICC World Twenty20 | 19 Jun 2009 |
| 4 | DR Martyn (Aus) | 96 | (56b) | SAf | Brisbane | Only Twenty20 International | 9 Jan 2006 |
| 5 | HH Gibbs (SAf) | 90* | (55b) | WI | Johannesburg | ICC World Twenty20 | 11 Sep 2007 |
| 6 | GC Smith (SAf) | 89* | (58b) | Aus | Johannesburg | Only Twenty20 International | 24 Feb 2006 |
| = | JM Kemp (SAf) | 89* | (56b) | NZ | Durban | ICC World Twenty20 | 19 Sep 2007 |
| 8 | DA Warner (Aus) | 89 | (43b) | SAf | Melbourne | 1st Twenty20 International | 11 Jan 2009 |
| 9 | DJ Hussey (Aus) | 88* | (44b) | SAf | Johannesburg | 1st Twenty20 International | 27 Mar 2009 |
| 10 | ST Jayasuriya (SL) | 88 | (44b) | Kenya | Johannesburg | ICC World Twenty20 | 14 Sep 2007 |
| = | CH Gayle (WI) | 88 | (50b) | Aus | The Oval | ICC World Twenty20 | 6 Jun 2009 |
| 12 | Misbah-ul-Haq (Pak) | 87* | (53b) | Bng | Karachi | Only Twenty20 International | 20 Apr 2008 |
| 13 | A Symonds (Aus) | 85* | (46b) | NZ | Perth | Only Twenty20 International | 11 Dec 2007 |
| 14 | Nazimuddin (Bng) | 81 | (50b) | Pak | Nairobi GG | Twenty20 Quadrangular (Kenya) | 2 Sep 2007 |
| = | ST Jayasuriya (SL) | 81 | (47b) | WI | Nottingham | ICC World Twenty20 | 10 Jun 2009 |
| 16 | AB de Villiers (SAf) | 79* | (34b) | Scot | The Oval | ICC World Twenty20 | 7 Jun 2009 |
| 17 | H Masakadza (Zim) | 79 | (52b) | Can | King City | T20 Canada | 13 Oct 2008 |
| = | PD Collingwood (Eng) | 79 | (41b) | WI | The Oval | 1st Twenty20 International | 28 Jun 2007 |
| = | KP Pietersen (Eng) | 79 | (37b) | Zim | Cape Town | ICC World Twenty20 | 13 Sep 2007 |
| 20 | DPMD Jayawardene (SL) | 78 | (53b) | Ire | Lord's | ICC World Twenty20 | 14 Jun 2009 |
| = | JP Duminy (SAf) | 78 | (48b) | Aus | Melbourne | 1st Twenty20 International | 11 Jan 2009 |
| 22 | LMP Simmons (WI) | 77 | (50b) | SAf | The Oval | ICC World Twenty20 | 13 Jun 2009 |
| 23 | RT Ponting (Aus) | 76 | (53b) | Ind | Mumbai BS | Only Twenty20 International | 20 Oct 2007 |
| 24 | G Gambhir (Ind) | 75 | (54b) | Pak | Johannesburg | ICC World Twenty20 | 24 Sep 2007 |
| 25 | Salman Butt (Pak) | 74 | (56b) | Can | King City | T20 Canada | 10 Oct 2008 |
Asterisk signifies not out
Bold signifies achievement less than 3 years old.
Date given refers to first day of match.